Melatonin pre-treatment mitigates SHSY-5Y cells against oxaliplatin induced mitochondrial stress and...
Melatonin pre-treatment mitigates SHSY-5Y cells against oxaliplatin induced mitochondrial stress and apoptotic cell death
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Oxaliplatin (Oxa) treatment to SH-SY5Y human neuroblastoma cells has been shown by previous studies to induce oxidative stress, which in turn modulates intracellular signaling cascades resulting in cell death. While this phenomenon of Oxa-induced neurotoxicity is known, the underlying mechanisms involved in this cell death cascade must be clarified...
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Full title
Melatonin pre-treatment mitigates SHSY-5Y cells against oxaliplatin induced mitochondrial stress and apoptotic cell death
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TN_cdi_plos_journals_1922176500
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1922176500
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0180953
