Generation and phenotypic characterization of Pde1a mutant mice
Generation and phenotypic characterization of Pde1a mutant mice
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
It has been proposed that a reduction in intracellular calcium causes an increase in intracellular cAMP and PKA activity through stimulation of calcium inhibitable adenylyl cyclase 6 and inhibition of phosphodiesterase 1 (PDE1), the main enzymes generating and degrading cAMP in the distal nephron and collecting duct, thus contributing to the develo...
Alternative Titles
Full title
Generation and phenotypic characterization of Pde1a mutant mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1923983036
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1923983036
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0181087
