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Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicro...

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927790044

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

About this item

Full title

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-08, Vol.12 (8), p.e0182926-e0182926

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Dermaseptin-B2 (DRS-B2) is a multifunctional cationic antimicrobial peptide (CAP) isolated from frog skin secretion. We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we evaluated the antiproliferative activity of DRS-B2 on numerous tumor cell lines, its cell internaliz...

Alternative Titles

Full title

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1927790044

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927790044

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0182926

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