Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and bl...
Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The effects of retinoids on adrenal aldosterone synthase gene (CYP11B2) expression and aldosterone secretion are still unknown. We therefore examined the effects of nuclear retinoid X receptor (RXR) pan-agonist PA024 on CYP11B2 expression, aldosterone secretion and blood pressure, to elucidate its potential as a novel anti-hypertensive drug. We dem...
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Full title
Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure
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TN_cdi_plos_journals_1927973112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927973112
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0181055
