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Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf...

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1928760129

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

About this item

Full title

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-08, Vol.12 (8), p.e0183166-e0183166

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

GPR116 (ADGRF5) and ELTD1 (ADGRL4) belong to different subfamilies of the adhesion G-protein-coupled receptor group but are both expressed in endothelial cells. We therefore analyzed their functions in mice lacking these receptors. While loss of GPR116 or ELTD1 alone had no obvious effect on cardiovascular or kidney function, mice lacking both, GPR...

Alternative Titles

Full title

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1928760129

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1928760129

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0183166

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