Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formati...
Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
A functioning gene drive system could fundamentally change our strategies for the control of vector-borne diseases by facilitating rapid dissemination of transgenes that prevent pathogen transmission or reduce vector capacity. CRISPR/Cas9 gene drive promises such a mechanism, which works by converting cells that are heterozygous for the drive const...
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Full title
Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations
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TN_cdi_plos_journals_1929370551
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1929370551
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1006796
