Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor reper...
Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequence rare. Yet unrelated individuals do share receptors, which together constitute a "public" repertoire of abundant clonotypes. The TCR repertoire is initially formed pren...
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Full title
Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires
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TN_cdi_plos_journals_1929417266
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1929417266
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1005572
