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Prickle1 regulates neurite outgrowth of apical spiral ganglion neurons but not hair cell polarity in...

Prickle1 regulates neurite outgrowth of apical spiral ganglion neurons but not hair cell polarity in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1932146090

Prickle1 regulates neurite outgrowth of apical spiral ganglion neurons but not hair cell polarity in the murine cochlea

About this item

Full title

Prickle1 regulates neurite outgrowth of apical spiral ganglion neurons but not hair cell polarity in the murine cochlea

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-08, Vol.12 (8), p.e0183773-e0183773

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In the mammalian organ of Corti (OC), the stereocilia on the apical surface of hair cells (HCs) are uniformly organized in a neural to abneural axis (or medial-laterally). This organization is regulated by planar cell polarity (PCP) signaling. Mutations of PCP genes, such as Vangl2, Dvl1/2, Celsr1, and Fzd3/6, affect the formation of HC orientation...

Alternative Titles

Full title

Prickle1 regulates neurite outgrowth of apical spiral ganglion neurons but not hair cell polarity in the murine cochlea

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1932146090

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1932146090

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0183773

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