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Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients...

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1936509689

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme

About this item

Full title

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-09, Vol.12 (9), p.e0181538

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Immune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) have been highly successful in the treatment of cancer. While PD-1 expression has been widely investigated, its role in CD4+ effector T cells in the setting of health and cancer remains unclear, particularly in the setting of glioblastoma multiforme (GBM), the most aggres...

Alternative Titles

Full title

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1936509689

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1936509689

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0181538

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