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Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with...

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1939435812

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases

About this item

Full title

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2017-08, Vol.13 (8), p.e1006998-e1006998

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The guidance cue UNC-6/Netrin regulates both attractive and repulsive axon guidance. Our previous work showed that in C. elegans, the attractive UNC-6/Netrin receptor UNC-40/DCC stimulates growth cone protrusion, and that the repulsive receptor, an UNC-5:UNC-40 heterodimer, inhibits growth cone protrusion. We have also shown that inhibition of grow...

Alternative Titles

Full title

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1939435812

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1939435812

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1006998

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