NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation
NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Regulation of our water homeostasis is fine-tuned by dynamic translocation of Aquaporin-2 (AQP2)-bearing vesicles to and from the plasma membrane of renal principal cells. Whereas binding of vasopressin to its type-2 receptor initiates a cAMP-protein kinase A cascade and AQP2 translocation to the apical membrane, this is counteracted by protein kin...
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Full title
NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation
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TN_cdi_plos_journals_1940904866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1940904866
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0183774
