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Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1941348931

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

About this item

Full title

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-09, Vol.12 (9), p.e0184473-e0184473

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Platelet-derived growth factor receptor alpha (PDGFRα) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors. Correct timing and level of Pdgfra expression is crucial for embryo development, and deletion of Pdgfra caused developmental defects of multiple endoderm and mesoderm derived structures, resulting in a complex pheno...

Alternative Titles

Full title

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1941348931

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1941348931

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0184473

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