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Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A p...

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1945719880

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

About this item

Full title

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-10, Vol.12 (10), p.e0185677-e0185677

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

HIV-1 induces changes in the miRNA expression profile of infected CD4+ T cells that could improve viral replication. HIV-1 regulator Tat modifies the cellular gene expression and has been appointed as an RNA silencing suppressor. Tat is a 101-residue protein codified by two exons that regulates the elongation of viral transcripts. The first exon of...

Alternative Titles

Full title

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1945719880

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1945719880

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0185677

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