Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling
Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Niemann-Pick Type C (NPC) disease is a neurodegenerative disease that is characterized by the accumulation of cholesterol and glycosphingolipids in the late endocytic pathway. The majority of NPC cases are due to mutations in the NPC1 gene. The precise function of this gene is not yet known.
Using cDNA microarrays, we analyzed the genome-wide ex...
Alternative Titles
Full title
Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1949665540
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1949665540
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0000019
