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DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and I...

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1950156566

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

About this item

Full title

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

Publisher

United States: Public Library of Science

Journal title

PloS one, 2007-09, Vol.2 (9), p.e895-e895

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The role of DNA cytosine methylation, an epigenetic regulator of chromatin structure and function, during normal and pathological brain development and aging remains unclear. Here, we examined by MethyLight PCR the DNA methylation status at 50 loci, encompassing primarily 5' CpG islands of genes related to CNS growth and development, in temporal ne...

Alternative Titles

Full title

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1950156566

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1950156566

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0000895

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