DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and I...
DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The role of DNA cytosine methylation, an epigenetic regulator of chromatin structure and function, during normal and pathological brain development and aging remains unclear. Here, we examined by MethyLight PCR the DNA methylation status at 50 loci, encompassing primarily 5' CpG islands of genes related to CNS growth and development, in temporal ne...
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DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons
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TN_cdi_plos_journals_1950156566
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1950156566
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0000895