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Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depressi...

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depressi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1953158083

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression

About this item

Full title

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-10, Vol.12 (10), p.e0186700

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

This study evaluated the chronic effects of fluoxetine, a commonly prescribed SSRI antidepressant, on the peripheral and central levels of inflammatory cytokines including IL-1β, IL-6, TNF-α and IL-17 over a 4-interval in a rat model of chronic mild stress (CMS) which resembles the human experience of depression. Twenty-four Sprague-Dawley rats wer...

Alternative Titles

Full title

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1953158083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1953158083

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0186700

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