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Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients...

Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959207658

Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency

About this item

Full title

Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0187266-e0187266

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Current evidence indicates that the common AMPD1 gene variant is associated with improved survival in patients with advanced heart failure. Whilst adenosine has been recognized to mediate the cardioprotective effect of C34T AMPD1, the precise pathophysiologic mechanism involved remains undefined to date. To address this issue, we used cardio-pulmon...

Alternative Titles

Full title

Effects of AMPD1 common mutation on the metabolic-chronotropic relationship: Insights from patients with myoadenylate deaminase deficiency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1959207658

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959207658

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0187266

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