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Distinct NG2 proteoglycan-dependent roles of resident microglia and bone marrow-derived macrophages...

Distinct NG2 proteoglycan-dependent roles of resident microglia and bone marrow-derived macrophages...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959211032

Distinct NG2 proteoglycan-dependent roles of resident microglia and bone marrow-derived macrophages during myelin damage and repair

About this item

Full title

Distinct NG2 proteoglycan-dependent roles of resident microglia and bone marrow-derived macrophages during myelin damage and repair

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0187530-e0187530

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We used a bone marrow transplantation approach to distinguish the activities of bone marrow-derived macrophages from the activities of central nervous system-resident microglia in phenomena associated with axon demyelination and remyelination. We transplanted wild type or germline NG2 null beta-actin-EGFP expressing bone marrow into irradiated wild...

Alternative Titles

Full title

Distinct NG2 proteoglycan-dependent roles of resident microglia and bone marrow-derived macrophages during myelin damage and repair

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1959211032

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959211032

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0187530

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