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Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and...

Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959228676

Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes

About this item

Full title

Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0187561-e0187561

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Endoplasmic reticulum (ER) stress is characterized by the accumulation of misfolded proteins due to an impairment of ER quality control pathways leading to the activation of a defense system, called unfolded protein response (UPR). While thyrocytes are supposed to be highly susceptible to environmental conditions that cause ER stress due to the syn...

Alternative Titles

Full title

Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1959228676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1959228676

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0187561

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