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Notch signaling and progenitor/ductular reaction in steatohepatitis

Notch signaling and progenitor/ductular reaction in steatohepatitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1964556854

Notch signaling and progenitor/ductular reaction in steatohepatitis

About this item

Full title

Notch signaling and progenitor/ductular reaction in steatohepatitis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0187384-e0187384

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Persistent hepatic progenitor cells (HPC) activation resulting in ductular reaction (DR) is responsible for pathologic liver repair in cholangiopathies. Also, HPC/DR expansion correlates with fibrosis in several chronic liver diseases, including steatohepatitis. Increasing evidence indicates Notch signaling as a key regulator of HPC/DR response in...

Alternative Titles

Full title

Notch signaling and progenitor/ductular reaction in steatohepatitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1964556854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1964556854

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0187384

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