Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subj...
Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subjects with seropositive rheumatoid arthritis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Anti-citrullinated protein antibodies (ACPA) have been shown to cause platelet activation in vitro, through the low-affinity immunoglobulin G (IgG) receptor (FcγRIIa) on platelets. Platelet activation via engagement of FcγRIIa results in proteolytic cleavage and shedding of platelet specific glycoprotein VI (GPVI) which can be detected in the plasm...
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Full title
Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subjects with seropositive rheumatoid arthritis
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TN_cdi_plos_journals_1964558276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1964558276
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0188027
