TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter
TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
HIV1-TAT interactive protein (TIP60) is a haploinsufficient tumor suppressor. However, the potential mechanisms endowing its tumor suppressor ability remain incompletely understood. It plays a vital role in virus-induced cancers where TIP60 down-regulates the expression of human papillomavirus (HPV) oncoprotein E6 which in turn destabilizes TIP60....
Alternative Titles
Full title
TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1965104558
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1965104558
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1006681
