Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signa...
Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Epigenetic mechanisms play important roles in the regulation of tumorigenesis, and hypoxia-induced epigenetic changes may be critical for the adaptation of cancer cells to the hypoxic microenvironment of solid tumors. Previously, we showed that loss-of-function of the hypoxia-regulated H3K9 methyltransferase G9A attenuates tumor growth. However, th...
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Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway
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TN_cdi_plos_journals_1965167166
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1965167166
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0188051