Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the...
Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120
About this item
Full title
Author / Creator
deCamp, Allan C. , Rolland, Morgane , Edlefsen, Paul T. , Sanders-Buell, Eric , Hall, Breana , Magaret, Craig A. , Fiore-Gartland, Andrew J. , Juraska, Michal , Carpp, Lindsay N. , Karuna, Shelly T. , Bose, Meera , LePore, Steven , Miller, Shana , O'Sullivan, Annemarie , Poltavee, Kultida , Bai, Hongjun , Dommaraju, Kalpana , Zhao, Hong , Wong, Kim , Chen, Lennie , Ahmed, Hasan , Goodman, Derrick , Tay, Matthew Z. , Gottardo, Raphael , Koup, Richard A. , Bailer, Robert , Mascola, John R. , Graham, Barney S. , Roederer, Mario , O’Connell, Robert J. , Michael, Nelson L. , Robb, Merlin L. , Adams, Elizabeth , D’Souza, Patricia , Kublin, James , Corey, Lawrence , Geraghty, Daniel E. , Frahm, Nicole , Tomaras, Georgia D. , McElrath, M. Juliana , Frenkel, Lisa , Styrchak, Sheila , Tovanabutra, Sodsai , Sobieszczyk, Magdalena E. , Hammer, Scott M. , Kim, Jerome H. , Mullins, James I. and Gilbert, Peter B.
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Although the HVTN 505 DNA/recombinant adenovirus type 5 vector HIV-1 vaccine trial showed no overall efficacy, analysis of breakthrough HIV-1 sequences in participants can help determine whether vaccine-induced immune responses impacted viruses that caused infection. We analyzed 480 HIV-1 genomes sampled from 27 vaccine and 20 placebo recipients an...
Alternative Titles
Full title
Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120
Authors, Artists and Contributors
Author / Creator
Rolland, Morgane
Edlefsen, Paul T.
Sanders-Buell, Eric
Hall, Breana
Magaret, Craig A.
Fiore-Gartland, Andrew J.
Juraska, Michal
Carpp, Lindsay N.
Karuna, Shelly T.
Bose, Meera
LePore, Steven
Miller, Shana
O'Sullivan, Annemarie
Poltavee, Kultida
Bai, Hongjun
Dommaraju, Kalpana
Zhao, Hong
Wong, Kim
Chen, Lennie
Ahmed, Hasan
Goodman, Derrick
Tay, Matthew Z.
Gottardo, Raphael
Koup, Richard A.
Bailer, Robert
Mascola, John R.
Graham, Barney S.
Roederer, Mario
O’Connell, Robert J.
Michael, Nelson L.
Robb, Merlin L.
Adams, Elizabeth
D’Souza, Patricia
Kublin, James
Corey, Lawrence
Geraghty, Daniel E.
Frahm, Nicole
Tomaras, Georgia D.
McElrath, M. Juliana
Frenkel, Lisa
Styrchak, Sheila
Tovanabutra, Sodsai
Sobieszczyk, Magdalena E.
Hammer, Scott M.
Kim, Jerome H.
Mullins, James I.
Gilbert, Peter B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1965590441
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1965590441
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0185959
