Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of...
Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of heme oxygenase
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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It has recently been shown that signal peptide peptidase (SPP) can catalyze the intramembrane cleavage of heme oxygenase-1 (HO-1) that leads to translocation of HO-1 into the cytosol and nucleus. While there is consensus that translocated HO-1 promotes tumor progression and drug resistance, the physiological signals leading to SPP-mediated intramem...
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Full title
Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of heme oxygenase
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TN_cdi_plos_journals_1966425752
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1966425752
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0188344
