Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases
Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Recent advances allow multiplexed genome engineering in E. coli, employing easily designed oligonucleotides to edit multiple loci simultaneously. A similar technology in human cells would greatly expedite functional genomics, both by enhancing our ability to test how individual variants such as single nucleotide polymorphisms (SNPs) are related to...
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Full title
Stable Gene Targeting in Human Cells Using Single-Strand Oligonucleotides with Modified Bases
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TN_cdi_plos_journals_1967987031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1967987031
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0036697
