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Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent s...

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1969919141

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10

About this item

Full title

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-11, Vol.12 (11), p.e0188584-e0188584

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Searching for new strategies for effective elimination of human prostate cancer cells, we investigated the cooperative cytotoxic action of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and two platinum-based complexes, cisplatin or LA-12, and related molecular mechanisms. We demonstrated a notable ability of cisplatin or LA-12 to...

Alternative Titles

Full title

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1969919141

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1969919141

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0188584

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