Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a M...
Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Multiple myeloma (MM), the second most common hematopoietic malignancy, remains an incurable plasma cell (PC) neoplasm. While the proteasome inhibitor, bortezomib (Bz) has increased patient survival, resistance represents a major treatment obstacle as most patients ultimately relapse becoming refractory to additional Bz therapy. Current tests fail...
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Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma
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TN_cdi_plos_journals_1975712075
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1975712075
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0077608