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Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a M...

Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a M...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1975712075

Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma

About this item

Full title

Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013, Vol.8 (10), p.e77608-e77608

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Multiple myeloma (MM), the second most common hematopoietic malignancy, remains an incurable plasma cell (PC) neoplasm. While the proteasome inhibitor, bortezomib (Bz) has increased patient survival, resistance represents a major treatment obstacle as most patients ultimately relapse becoming refractory to additional Bz therapy. Current tests fail...

Alternative Titles

Full title

Bortezomib Resistance Can Be Reversed by Induced Expression of Plasma Cell Maturation Markers in a Mouse In Vitro Model of Multiple Myeloma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1975712075

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1975712075

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0077608

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