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Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic s...

Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1976001350

Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

About this item

Full title

Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-12, Vol.12 (12), p.e0188569-e0188569

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Numerous groups have documented that Ascorbic Acid (AA) promotes cardiomyocyte differentiation from both mouse and human ESCs and iPSCs. AA is now considered indispensable for the routine production of hPSC-cardiomyocytes (CMs) using defined media; however, the mechanisms involved with the inductive process are poorly understood. Using a geneticall...

Alternative Titles

Full title

Ascorbic acid promotes cardiomyogenesis through SMAD1 signaling in differentiating mouse embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1976001350

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1976001350

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0188569

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