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Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1977446509

Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

About this item

Full title

Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-01, Vol.9 (1), p.e87621

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Preeclampsia (PE) is characterized by exaggerated apoptosis of the villous trophoblast of placental villi. Since p53 is a critical regulator of apoptosis we hypothesized that excessive apoptosis in PE is mediated by abnormal expression of proteins participating in the p53 pathway and that modulation of the p53 pathway alters trophoblast apoptosis i...

Alternative Titles

Full title

Preeclampsia Is Associated with Alterations in the p53-Pathway in Villous Trophoblast

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1977446509

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1977446509

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0087621

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