Evidence for Aberrant Astrocyte Hemichannel Activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNC...
Evidence for Aberrant Astrocyte Hemichannel Activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Juvenile Neuronal Ceroid Lipofuscinosis (JNCL) is a lysosomal storage disease caused by an autosomal recessive mutation in CLN3 that leads to vision loss, progressive cognitive and motor decline, and premature death. Morphological evidence of astrocyte activation occurs early in the disease process and coincides with regions where neuronal loss eve...
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Full title
Evidence for Aberrant Astrocyte Hemichannel Activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)
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TN_cdi_plos_journals_1977746451
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1977746451
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0095023
