AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucos...
AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
PI3K/AKT pathway alterations are associated with incomplete response to chemoradiation in human cervical cancer. This study was performed to test for mutations in the PI3K pathway and to evaluate the effects of AKT inhibitors on glucose uptake and cell viability.
Mutational analysis of DNA from 140 pretreatment tumor biopsies and 8 human cervica...
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Full title
AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake
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TN_cdi_plos_journals_1977747211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1977747211
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0092948
