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Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1978299194

Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

About this item

Full title

Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

Author / Creator

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-12, Vol.12 (12), p.e0189221-e0189221

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Claudin-2, ZO-1, and occludin are major components of tight junctions (TJs) in the proximal tubule. However, their roles in maintaining paracellular permeability as leaky epithelia have yet to be defined.
To investigate the contributory role of TJ proteins in the leaky proximal tubule, we xamined the effect of inhibiting claudin-2, occludin, and...

Alternative Titles

Full title

Roles of claudin-2, ZO-1 and occludin in leaky HK-2 cells

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1978299194

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1978299194

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0189221

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