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Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo...

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1979936976

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions

About this item

Full title

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-11, Vol.9 (11), p.e112339-e112339

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Intranasal treatment with C57BL/6 MSCs reduces lesion volume and improves motor and cognitive behavior in the neonatal hypoxic-ischemic (HI) mouse model. In this study, we investigated the potential of human MSCs (hMSCs) to treat HI brain injury in the neonatal mouse. Assessing the regenerative capacity of hMSCs is crucial for translation of our kn...

Alternative Titles

Full title

Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1979936976

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1979936976

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0112339

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