New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease
New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The causes of Parkinson disease (PD) remain mysterious, although some evidence supports mitochondrial dysfunctions and α-synuclein accumulation in Lewy bodies as major events. The abnormal accumulation of α-synuclein has been associated with a deficiency in the ubiquitin-proteasome system and the autophagy-lysosomal pathway. Cathepsin D (cathD), th...
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New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease
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TN_cdi_plos_journals_1980707355
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1980707355
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0116641
