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An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human C...

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human C...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1982585887

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells

About this item

Full title

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-05, Vol.10 (5), p.e0126159-e0126159

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

More information

Scope and Contents

Contents

Multidrug resistant cancer cells are hard to eradicate for the inefficacy of conventional anticancer drugs. Besides escaping the cytotoxic effects of chemotherapy, they also bypass the pro-immunogenic effects induced by anticancer drugs: indeed they are not well recognized by host dendritic cells and do not elicit a durable anti-tumor immunity. It...

Alternative Titles

Full title

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1982585887

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1982585887

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0126159

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