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Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tube...

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tube...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1983422631

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis

About this item

Full title

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-02, Vol.9 (2), p.e87909

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The reductively activated nitroaromatic class of antimicrobials, which include nitroimidazole and the more metabolically labile nitrofuran antitubercular agents, have demonstrated some potential for development as therapeutics against dormant TB bacilli. In previous studies, the pharmacokinetic properties of nitrofuranyl isoxazolines were improved...

Alternative Titles

Full title

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1983422631

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1983422631

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0087909

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