Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57B...
Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The reduction of functional β cell mass is a key feature of type 2 diabetes. Here, we studied metabolic functions and islet gene expression profiles of C57BL/6J mice with naturally occurring nicotinamide nucleotide transhydrogenase (NNT) deletion mutation, a widely used model of diet-induced obesity and diabetes. On high fat diet (HF), the mice dev...
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Full title
Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice
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TN_cdi_plos_journals_1983424265
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1983424265
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086815
