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Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diab...

Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diab...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1984975474

Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation

About this item

Full title

Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-06, Vol.9 (6), p.e100562

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Several studies indicated that type 2 diabetes mellitus and insulin resistance are associated with increased colon cancer risk. Recently, studies suggest that metformin can reduce cancer risk in diabetic or non-diabetic patients with unclear mechanisms. This work aimed to determine the effect of metformin on chemically-induced colon cancer in mice....

Alternative Titles

Full title

Role of metformin in suppressing 1,2-dimethylhydrazine-induced colon cancer in diabetic and non-diabetic mice: effect on tumor angiogenesis and cell proliferation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1984975474

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1984975474

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0100562

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