Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire
Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire
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Author / Creator
Liu, Xiao , Zhang, Wei , Zeng, Xiaojing , Zhang, Ruifang , Du, Yuanping , Hong, Xueyu , Cao, Hongzhi , Su, Zheng , Wang, Changxi , Wu, Jinghua , Nie, Chao , Xu, Xun and Kristiansen, Karsten
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
High-throughput sequencing has recently been applied to profile the high diversity of antibodyome/B cell receptors (BCRs) and T cell receptors (TCRs) among immune cells. To date, Multiplex PCR (MPCR) and 5'RACE are predominately used to enrich rearranged BCRs and TCRs. Both approaches have advantages and disadvantages; however, a systematic evaluat...
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Full title
Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire
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TN_cdi_plos_journals_1986261862
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1986261862
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0152464
