Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
During obesity, adipose tissue macrophages (ATM) are increased in concert with local inflammation and insulin resistance. Since the levels of sphingolipid (SLs) in adipose tissue (AT) are altered during obesity we investigated the potential impact of SLs on ATMs. For this, we first analyzed expression of SL metabolizing genes in ATMs isolated from...
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Full title
Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
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TN_cdi_plos_journals_1991550532
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1991550532
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0182075
