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Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10...

Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1993570971

Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

About this item

Full title

Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-08, Vol.7 (8), p.e43588-e43588

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Sarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved. Plasmatic hypergammaglobulinemia and B cell accumulation in granulomatous lesions suggest the possible role of humoral immune responses in the pathogenesis of sarcoidosis. The purpose of this study...

Alternative Titles

Full title

Active Chronic Sarcoidosis is Characterized by Increased Transitional Blood B Cells, Increased IL-10-Producing Regulatory B Cells and High BAFF Levels

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1993570971

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1993570971

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0043588

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