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Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation o...

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619058

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

About this item

Full title

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006769

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Detection of viral nucleic acids plays a critical role in the induction of intracellular host immune defences. However, the temporal recruitment of immune regulators to infecting viral genomes remains poorly defined due to the technical difficulties associated with low genome copy-number detection. Here we utilize 5-Ethynyl-2'-deoxyuridine (EdU) la...

Alternative Titles

Full title

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2002619058

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619058

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1006769

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