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Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619062

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

About this item

Full title

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2018-01, Vol.16 (1), p.e2004411

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The AP-5 adaptor protein complex is presumed to function in membrane traffic, but so far nothing is known about its pathway or its cargo. We have used CRISPR-Cas9 to knock out the AP-5 ζ subunit gene, AP5Z1, in HeLa cells, and then analysed the phenotype by subcellular fractionation profiling and quantitative mass spectrometry. The retromer complex...

Alternative Titles

Full title

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2002619062

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619062

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.2004411

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