Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endoso...
Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The cellular PI3K/Akt and/or MEK/ERK signaling pathways mediate the entry process or endosomal acidification during infection of many viruses. However, their roles in the early infection events of group A rotaviruses (RVAs) have remained elusive. Here, we show that late-penetration (L-P) human DS-1 and bovine NCDV RVA strains stimulate these signal...
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Full title
Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating
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TN_cdi_plos_journals_2002619290
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619290
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1006820
