A dystrophic Duchenne mouse model for testing human antisense oligonucleotides
A dystrophic Duchenne mouse model for testing human antisense oligonucleotides
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Full title
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease generally caused by reading frame disrupting mutations in the DMD gene resulting in loss of functional dystrophin protein. The reading frame can be restored by antisense oligonucleotide (AON)-mediated exon skipping, allowing production of internally deleted, but partially function...
Alternative Titles
Full title
A dystrophic Duchenne mouse model for testing human antisense oligonucleotides
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Record Identifier
TN_cdi_plos_journals_2007098608
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2007098608
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0193289
