CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
CR6 interacting factor 1 (CRIF1) deficiency impairs mitochondrial oxidative phosphorylation complexes, contributing to increased mitochondrial and cellular reactive oxygen species (ROS) production. CRIF1 downregulation has also been revealed to decrease sirtuin 1 (SIRT1) expression and impair vascular function. Inhibition of SIRT1 disturbs oxidativ...
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Full title
CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
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TN_cdi_plos_journals_2007691134
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2007691134
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0192693
