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Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumato...

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumato...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2009229585

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

About this item

Full title

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

Publisher

United States: Public Library of Science

Journal title

PloS one, 2018-02, Vol.13 (2), p.e0192704-e0192704

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown remarkable efficacy in multiple cancer types, concomitant with immune-related adverse events, including arthralgia and inflammato...

Alternative Titles

Full title

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2009229585

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2009229585

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0192704

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