Expansion of human and murine hematopoietic stem and progenitor cells ex vivo without genetic modifi...
Expansion of human and murine hematopoietic stem and progenitor cells ex vivo without genetic modification using MYC and Bcl-2 fusion proteins
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The long-term repopulating hematopoietic stem cell (HSC) population can self-renew in vivo, support hematopoiesis for the lifetime of the individual, and is of critical importance in the context of bone marrow stem cell transplantation. The mechanisms that regulate the expansion of HSCs in vivo and in vitro remain unclear to date. Since the current...
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Expansion of human and murine hematopoietic stem and progenitor cells ex vivo without genetic modification using MYC and Bcl-2 fusion proteins
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TN_cdi_plos_journals_2014436207
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014436207
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0105525