Identification of FAM173B as a protein methyltransferase promoting chronic pain
Identification of FAM173B as a protein methyltransferase promoting chronic pain
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Author / Creator
Willemen, Hanneke L. D. M. , Kavelaars, Annemieke , Prado, Judith , Maas, Mirjam , Versteeg, Sabine , Nellissen, Lara J. J. , Tromp, Jeshua , Gonzalez Cano, Rafael , Zhou, Wenjun , Jakobsson, Magnus E. , Małecki, Jędrzej , Posthuma, George , Habib, Abdella M. , Heijnen, Cobi J. , Falnes, Pål Ø. and Eijkelkamp, Niels
Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Chronic pain is a debilitating problem, and insights in the neurobiology of chronic pain are needed for the development of novel pain therapies. A genome-wide association study implicated the 5p15.2 region in chronic widespread pain. This region includes the coding region for FAM173B, a functionally uncharacterized protein. We demonstrate here that...
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Full title
Identification of FAM173B as a protein methyltransferase promoting chronic pain
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TN_cdi_plos_journals_2014496063
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014496063
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.2003452